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Activated Abl kinase inhibits oncogenic transforming growth factor-β signaling and tumorigenesis in mammary tumors
Transforming growth factor-β (TGF-β) is a ubiquitous cytokine with dual roles in tumor suppression and promotion, and these dichotomous functions have frustrated the development of therapies targeting oncogenic signaling by TGF-β. In comparison, Abl is well established as an initiator of hematopoiet...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Federation of American Societies for Experimental Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812049/ https://ncbi.nlm.nih.gov/pubmed/19690215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-138412 |
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