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β(3) Integrin and Src facilitate transforming growth factor-β mediated induction of epithelial-mesenchymal transition in mammary epithelial cells

INTRODUCTION: Transforming growth factor (TGF)-β suppresses breast cancer formation by preventing cell cycle progression in mammary epithelial cells (MECs). During the course of mammary tumorigenesis, genetic and epigenetic changes negate the cytostatic actions of TGF-β, thus enabling TGF-β to promo...

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Detalhes bibliográficos
Main Authors: Galliher, Amy J, Schiemann, William P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779461/
https://ncbi.nlm.nih.gov/pubmed/16859511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1524
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