The use of cystatin C to inhibit epithelial–mesenchymal transition and morphological transformation stimulated by transforming growth factor-β

INTRODUCTION: Transforming growth factor-β (TGF-β) is a potent suppressor of mammary epithelial cell (MEC) proliferation and is thus an inhibitor of mammary tumor formation. Malignant MECs typically evolve resistance to TGF-β-mediated growth arrest, enhancing their proliferation, invasion, and metas...

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Bibliographic Details
Main Authors: Sokol, Jonathan P, Neil, Jason R, Schiemann, Barbara J, Schiemann, William P
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242164/
https://ncbi.nlm.nih.gov/pubmed/16168131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1312
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