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Grb2 Binding to Tyr284 in TβR-II is Essential for Mammary Tumor Growth and Metastasis Stimulated by TGF-β
We demonstrated previously that growth factor receptor bound protein 2 (Grb2) associates with the TGF-β type II receptor (TβR-II) upon its phosphorylation on Tyr284 by Src. Although this phosphotransferase reaction is critical in mediating TGF-β stimulation of epithelial-mesenchymal transition (EMT)...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615477/ https://ncbi.nlm.nih.gov/pubmed/18174260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgm245 |
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