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ERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function

Most (80%) of the triple-negative breast cancers (TNBCs) express mutant p53 proteins that acquire oncogenic activities including promoting metastasis. We previously showed that wild-type ERβ (ERβ1) impedes epithelial to mesenchymal transition (EMT) and decreases the invasiveness of TNBC cells. In th...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bado, Igor, Nikolos, Fotis, Rajapaksa, Gayani, Gustafsson, Jan-Åke, Thomas, Christoforos
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924664/
https://ncbi.nlm.nih.gov/pubmed/26871946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7300
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