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ERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function
Most (80%) of the triple-negative breast cancers (TNBCs) express mutant p53 proteins that acquire oncogenic activities including promoting metastasis. We previously showed that wild-type ERβ (ERβ1) impedes epithelial to mesenchymal transition (EMT) and decreases the invasiveness of TNBC cells. In th...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4924664/ https://ncbi.nlm.nih.gov/pubmed/26871946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7300 |
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