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MicroRNA-195 prevents dendritic degeneration and neuron death in rats following chronic brain hypoperfusion

Impaired synaptic plasticity and neuron loss are hallmarks of Alzheimer’s disease and vascular dementia. Here, we found that chronic brain hypoperfusion (CBH) by bilateral common carotid artery occlusion (2VO) decreased the total length, numbers and crossings of dendrites and caused neuron death in...

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Библиографические подробности
Опубликовано в: :Cell Death Dis
Главные авторы: Chen, Xin, Jiang, Xue-Mei, Zhao, Lin-Jing, Sun, Lin-Lin, Yan, Mei-Ling, Tian, You, Zhang, Shuai, Duan, Ming-Jing, Zhao, Hong-Mei, Li, Wen-Rui, Hao, Yang-Yang, Wang, Li-Bo, Xiong, Qiao-Jie, Ai, Jing
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520902/
https://ncbi.nlm.nih.gov/pubmed/28569780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.243
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