MicroRNA-195 prevents dendritic degeneration and neuron death in rats following chronic brain hypoperfusion

Impaired synaptic plasticity and neuron loss are hallmarks of Alzheimer’s disease and vascular dementia. Here, we found that chronic brain hypoperfusion (CBH) by bilateral common carotid artery occlusion (2VO) decreased the total length, numbers and crossings of dendrites and caused neuron death in...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Chen, Xin, Jiang, Xue-Mei, Zhao, Lin-Jing, Sun, Lin-Lin, Yan, Mei-Ling, Tian, You, Zhang, Shuai, Duan, Ming-Jing, Zhao, Hong-Mei, Li, Wen-Rui, Hao, Yang-Yang, Wang, Li-Bo, Xiong, Qiao-Jie, Ai, Jing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520902/
https://ncbi.nlm.nih.gov/pubmed/28569780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.243
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