MicroRNA-195 prevents dendritic degeneration and neuron death in rats following chronic brain hypoperfusion

Impaired synaptic plasticity and neuron loss are hallmarks of Alzheimer’s disease and vascular dementia. Here, we found that chronic brain hypoperfusion (CBH) by bilateral common carotid artery occlusion (2VO) decreased the total length, numbers and crossings of dendrites and caused neuron death in...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Chen, Xin, Jiang, Xue-Mei, Zhao, Lin-Jing, Sun, Lin-Lin, Yan, Mei-Ling, Tian, You, Zhang, Shuai, Duan, Ming-Jing, Zhao, Hong-Mei, Li, Wen-Rui, Hao, Yang-Yang, Wang, Li-Bo, Xiong, Qiao-Jie, Ai, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520902/
https://ncbi.nlm.nih.gov/pubmed/28569780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.243
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