MicroRNA-195 Protects Against Dementia Induced by Chronic Brain Hypoperfusion via Its Anti-Amyloidogenic Effect in Rats

Previous studies have demonstrated that chronic brain hypoperfusion (CBH) causes Aβ aggregation by upregulating expression of amyloid precursor protein (APP) and β-site APP cleaving enzyme 1 (BACE1) protein, which is accompanied by cognitive impairment, but the mechanisms are not fully understood. I...

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Vydáno v:J Neurosci
Hlavní autoři: Ai, Jing, Sun, Li-Hua, Che, Hui, Zhang, Rong, Zhang, Tian-Zhu, Wu, Wan-Chen, Su, Xiao-Lin, Chen, Xin, Yang, Guang, Li, Kang, Wang, Ning, Ban, Tao, Bao, Ya-Nan, Guo, Fei, Niu, Hui-Fang, Zhu, Yu-Lan, Zhu, Xiu-Ying, Zhao, Shi-Guang, Yang, Bao-Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619292/
https://ncbi.nlm.nih.gov/pubmed/23447608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1997-12.2013
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