Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia.

The tal-1 gene is altered as a consequence of the t(1;14) (p32;q11) chromosome translocation observed in 3% of patients with T cell acute lymphoblastic leukemia (T-ALL). tal-1 encodes a helix-loop-helix (HLH) domain, a DNA binding and dimerization motif found in a number of proteins involved in cell...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Brown, L, Cheng, J T, Chen, Q, Siciliano, M J, Crist, W, Buchanan, G, Baer, R
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1990
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552072/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2209547/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07535.x
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