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Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia.

The tal-1 gene is altered as a consequence of the t(1;14) (p32;q11) chromosome translocation observed in 3% of patients with T cell acute lymphoblastic leukemia (T-ALL). tal-1 encodes a helix-loop-helix (HLH) domain, a DNA binding and dimerization motif found in a number of proteins involved in cell...

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Bibliografski detalji
Glavni autori: Brown, L, Cheng, J T, Chen, Q, Siciliano, M J, Crist, W, Buchanan, G, Baer, R
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC552072/
https://ncbi.nlm.nih.gov/pubmed/2209547
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