Ubiquitylation of MFHAS1 by the ubiquitin ligase praja2 promotes M1 macrophage polarization by activating JNK and p38 pathways

Sepsis is a systemic inflammation caused by infection. The balance between M1–M2 macrophage polarization has an essential role in the pathogenesis of sepsis. However, the exact mechanism underlying macrophage polarization is unclear. We previously showed that levels of malignant fibrous histiocytoma...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Zhong, Jing, Wang, Huihui, Chen, Wankun, Sun, Zhirong, Chen, Jiawei, Xu, Yajun, Weng, Meilin, Shi, Qiqing, Ma, Duan, Miao, Changhong
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520684/
https://ncbi.nlm.nih.gov/pubmed/28471450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.102
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