Regulator of G protein signaling 2 is a key regulator of pancreatic β-cell mass and function

Pancreatic β-cell death and dysfunction contributes to the pathogenesis of both type 1 and type 2 diabetes. We aimed to examine whether the regulator of G protein signaling protein 2 (RGS2), a multifunctional inhibitor of G protein-coupled receptor (GPCR) signaling, impacts β-cell death and function...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Dong, H, Zhang, Y, Wang, J, Kim, D S, Wu, H, Sjögren, B, Gao, W, Luttrell, L, Wang, H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520679/
https://ncbi.nlm.nih.gov/pubmed/28542139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.216
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