GRP94 Is an Essential Regulator of Pancreatic β-Cell Development, Mass, and Function in Male Mice

Deficiencies in pancreatic β-cell mass contribute to both type 1 and type 2 diabetes. We investigated the role of the glucose-regulated protein (GRP) 94, an endoplasmic reticulum protein abundantly expressed in the pancreatic acini and islets, in β-cell development, survival, and function. We used a...

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Vydáno v:Endocrinology
Hlavní autoři: Kim, Do-sung, Song, Lili, Wang, Jingjing, Wu, Hongju, Gu, Guoqiang, Sugi, Yukiko, Li, Zihai, Wang, Hongjun
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2017
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793778/
https://ncbi.nlm.nih.gov/pubmed/29272356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00685
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