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Molecular design and synthesis of self-assembling camptothecin drug amphiphiles

The conjugation of small molecular hydrophobic anticancer drugs onto a short peptide with overall hydrophilicity to create self-assembling drug amphiphiles offers a new prodrug strategy, producing well-defined, discrete nanostructures with a high and quantitative drug loading. Here we show the detai...

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Bibliografske podrobnosti
izdano v:Acta Pharmacol Sin
Main Authors: Cheetham, Andrew G, Lin, Yi-an, Lin, Ran, Cui, Honggang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520181/
https://ncbi.nlm.nih.gov/pubmed/28260797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.151
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