Supramolecular Crafting of Self-Assembling Camptothecin Prodrugs with Enhanced Efficacy against Primary Cancer Cells

Chemical modification of small molecule hydrophobic drugs is a clinically proven strategy to devise prodrugs with enhanced treatment efficacy. While this prodrug strategy improves the parent drug's water solubility and pharmacokinetic profile, it typically compromises the drug's potency ag...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Theranostics
Päätekijät: Su, Hao, Zhang, Pengcheng, Cheetham, Andrew G, Koo, Jin Mo, Lin, Ran, Masood, Asad, Schiapparelli, Paula, Quiñones-Hinojosa, Alfredo, Cui, Honggang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ivyspring International Publisher 2016
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876630/
https://ncbi.nlm.nih.gov/pubmed/27217839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.15420
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