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The Self-Assembling Camptothecin-Tocopherol Prodrug: An Effective Approach for Formulating Camptothecin
Camptothecin (CPT) is a potent antitumor agent and functions via inhibiting the activity of topoisomerase I during DNA replication. However, the clinical application of CPT has been greatly hindered by its extremely poor solubility, the instability of its active lactone ring in blood stream, as well...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Biomaterials |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4470812/ https://ncbi.nlm.nih.gov/pubmed/26057133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.05.046 |
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