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The Self-Assembling Camptothecin-Tocopherol Prodrug: An Effective Approach for Formulating Camptothecin

Camptothecin (CPT) is a potent antitumor agent and functions via inhibiting the activity of topoisomerase I during DNA replication. However, the clinical application of CPT has been greatly hindered by its extremely poor solubility, the instability of its active lactone ring in blood stream, as well...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biomaterials
Päätekijät: Lu, Jianqin, Liu, Chuang, Wang, Pengcheng, Ghazwani, Mohammed, Xu, Jieni, Huang, Yixian, Ma, Xiaochao, Zhang, Peijun, Li, Song
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470812/
https://ncbi.nlm.nih.gov/pubmed/26057133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.05.046
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