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Linker-Determined Drug Release Mechanism of Free Camptothecin from Self-Assembling Drug Amphiphiles()

We report here that the release mechanism of free camptothecin from self-assembling drug amphiphiles can be regulated by use of different linker groups. Our results highlight the significance of the linker group of drug amphiphiles on the drug release efficiency and their consequent in vitro efficac...

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Detalhes bibliográficos
Main Authors: Cheetham, Andrew G., Ou, Yu-Chuan, Zhang, Pengcheng, Cui, Honggang
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160079/
https://ncbi.nlm.nih.gov/pubmed/24769796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc49453e
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