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CYLD, A20 and OTULIN deubiquitinases in NF-κB signaling and cell death: so similar, yet so different

Polyubiquitination of proteins has a pivotal role in the regulation of numerous cellular functions such as protein degradation, DNA repair and cell signaling. As deregulation of these processes can result in pathological conditions such as inflammatory diseases, neurodegeneration or cancer, tight re...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Lork, Marie, Verhelst, Kelly, Beyaert, Rudi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520167/
https://ncbi.nlm.nih.gov/pubmed/28362430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.46
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