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The role of hybrid ubiquitin chains in the MyD88 and other innate immune signalling pathways
The adaptor protein MyD88 is required for signal transmission by toll-like receptors and receptors of the interleukin-1 family of cytokines. MyD88 signalling triggers the formation of Lys63-linked and Met1-linked ubiquitin (K63-Ub, M1-Ub) chains within minutes. The K63-Ub chains, which are formed by...
Shranjeno v:
| izdano v: | Cell Death Differ |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5520163/ https://ncbi.nlm.nih.gov/pubmed/28475177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.17 |
| Oznake: |
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