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miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation

Basal autophagy is tightly regulated by transcriptional and epigenetic factors to maintain cellular homeostasis. Dysregulation of cardiac autophagy is associated with heart diseases, including cardiac hypertrophy, but the mechanism governing cardiac autophagy is rarely identified. To analyze the in...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell Death Differ
Hauptverfasser: Li, Z, Song, Y, Liu, L, Hou, N, An, X, Zhan, D, Li, Y, Zhou, L, Li, P, Yu, L, Xia, J, Zhang, Y, Wang, J, Yang, X
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520159/
https://ncbi.nlm.nih.gov/pubmed/26160071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.95
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