miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation

Basal autophagy is tightly regulated by transcriptional and epigenetic factors to maintain cellular homeostasis. Dysregulation of cardiac autophagy is associated with heart diseases, including cardiac hypertrophy, but the mechanism governing cardiac autophagy is rarely identified. To analyze the in...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Li, Z, Song, Y, Liu, L, Hou, N, An, X, Zhan, D, Li, Y, Zhou, L, Li, P, Yu, L, Xia, J, Zhang, Y, Wang, J, Yang, X
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520159/
https://ncbi.nlm.nih.gov/pubmed/26160071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.95
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