TSC complex decrease the expression of mTOR by regulated miR-199b-3p

Abstract The TSC complex formed by TSC1 and TSC2 is the most important upstream negative regulator of mTORC1. Genetic variations in either TSC1 or TSC2 cause tuberous sclerosis complex (TSC) disease which is a rare autosomal dominant disorder resulting in impairment of multiple organ systems. In thi...

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Principais autores:	Na Zhao, Qiuhong Xiong, Ping Li, Guangxin Chen, Han Xiao, Changxin Wu
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2025-01-01
Serija:	Scientific Reports
Teme:	TSC1 TSC2 MTOR MiR-199b-3p TSC
Online dostop:	https://doi.org/10.1038/s41598-025-85706-8
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