MSTN Attenuates Cardiac Hypertrophy through Inhibition of Excessive Cardiac Autophagy by Blocking AMPK /mTOR and miR-128/PPARγ/NF-κB

Cardiac hypertrophy, a response of the heart to increased workload, is a major risk factor for heart failure. Myostatin (MSTN) is an inhibitor of myogenesis, regulating the number and size of skeletal myocytes. In recent years, cardiomyocyte autophagy also has been considered to be involved in contr...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Ther Nucleic Acids
Main Authors: Qi, Hanping, Ren, Jing, Ba, Lina, Song, Chao, Zhang, Qianhui, Cao, Yonggang, Shi, Pilong, Fu, Bowen, Liu, Yongsheng, Sun, Hongli
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Gene & Cell Therapy 2019
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951838/
https://ncbi.nlm.nih.gov/pubmed/31923740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.12.003
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