Glucosylceramide Synthase Is Involved in Development of Invariant Natural Killer T Cells

Invariant natural killer T (iNKT) cells represent a unique population of CD1d-restricted T lymphocytes expressing an invariant T cell receptor encoded by Vα14-Jα18 and Vα24-Jα18 gene segments in mice and humans, respectively. Recognition of CD1d-loaded endogenous lipid antigen(s) on CD4/CD8-double p...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Popovic, Zoran V., Rabionet, Mariona, Jennemann, Richard, Krunic, Damir, Sandhoff, Roger, Gröne, Hermann-Josef, Porubsky, Stefan
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519558/
https://ncbi.nlm.nih.gov/pubmed/28785267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00848
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