Inhibition of hepatocellular carcinoma growth by blockade of glycosphingolipid synthesis

Hepatocellular carcinoma (HCC) is one of the most frequent cancers. In vitro studies suggest that growth and response to therapy of human carcinomas may depend on glycosphingolipid (GSL) expression. Glucosylceramide synthase (GCS), encoded by the gene Ugcg, is the basic enzyme required for the synth...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Jennemann, Richard, Federico, Giuseppina, Mathow, Daniel, Rabionet, Mariona, Rampoldi, Francesca, Popovic, Zoran V., Volz, Martina, Hielscher, Thomas, Sandhoff, Roger, Gröne, Hermann-Josef
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2017
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752514/
https://ncbi.nlm.nih.gov/pubmed/29312601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22648
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