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Inhibition of hepatocellular carcinoma growth by blockade of glycosphingolipid synthesis
Hepatocellular carcinoma (HCC) is one of the most frequent cancers. In vitro studies suggest that growth and response to therapy of human carcinomas may depend on glycosphingolipid (GSL) expression. Glucosylceramide synthase (GCS), encoded by the gene Ugcg, is the basic enzyme required for the synth...
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| Foilsithe in: | Oncotarget |
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| Main Authors: | , , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Impact Journals LLC
2017
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752514/ https://ncbi.nlm.nih.gov/pubmed/29312601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22648 |
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