Inhibition of hepatocellular carcinoma growth by blockade of glycosphingolipid synthesis

Hepatocellular carcinoma (HCC) is one of the most frequent cancers. In vitro studies suggest that growth and response to therapy of human carcinomas may depend on glycosphingolipid (GSL) expression. Glucosylceramide synthase (GCS), encoded by the gene Ugcg, is the basic enzyme required for the synth...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Jennemann, Richard, Federico, Giuseppina, Mathow, Daniel, Rabionet, Mariona, Rampoldi, Francesca, Popovic, Zoran V., Volz, Martina, Hielscher, Thomas, Sandhoff, Roger, Gröne, Hermann-Josef
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752514/
https://ncbi.nlm.nih.gov/pubmed/29312601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22648
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