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Autophagy inhibitor 3-methyladenine alleviates overload-exercise-induced cardiac injury in rats
Overload-exercise (OE) causes myocardial injury through inducing autophagy and apoptosis. In this study we examined whether an autophagy inhibitor 3-methyladenine (3-MA) could alleviate OE-induced cardiac injury. Rats were injected with 3-MA (15 mg/kg, iv) or saline before subjected to various inten...
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| Pubblicato in: | Acta Pharmacol Sin |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5519243/ https://ncbi.nlm.nih.gov/pubmed/28260802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.169 |
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