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Role of autophagy in the progression of osteoarthritis: The autophagy inhibitor, 3-methyladenine, aggravates the severity of experimental osteoarthritis

Accumulating evidence suggests that autophagy is closely related to the pathogenesis of osteoarthritis (OA). The aim of this study was to determine the changes in autophagy during the progression of OA and to elucidate the specific role of autophagy in OA. For this purpose, a cellular model of OA wa...

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Publicat a:Int J Mol Med
Autors principals: Cheng, Ni-Tao, Meng, Hai, Ma, Li-Feng, Zhang, Liang, Yu, Hao-Miao, Wang, Zhen-Zhong, Guo, Ai
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403511/
https://ncbi.nlm.nih.gov/pubmed/28339018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.2934
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