Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

OBJECTIVE: Augmenting nicotinamide adenine dinucleotide (NAD(+)) availability may protect skeletal muscle from age-related metabolic decline. Dietary supplementation of NAD(+) precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) appear efficacious in elevating muscle NAD(+). H...

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Bibliografiske detaljer
Udgivet i:Mol Metab
Main Authors: Fletcher, Rachel S., Ratajczak, Joanna, Doig, Craig L., Oakey, Lucy A., Callingham, Rebecca, Da Silva Xavier, Gabriella, Garten, Antje, Elhassan, Yasir S., Redpath, Philip, Migaud, Marie E., Philp, Andrew, Brenner, Charles, Canto, Carles, Lavery, Gareth G.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518663/
https://ncbi.nlm.nih.gov/pubmed/28752046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.05.011
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