Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

OBJECTIVE: Augmenting nicotinamide adenine dinucleotide (NAD(+)) availability may protect skeletal muscle from age-related metabolic decline. Dietary supplementation of NAD(+) precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) appear efficacious in elevating muscle NAD(+). H...

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Bibliografske podrobnosti
izdano v:Mol Metab
Main Authors: Fletcher, Rachel S., Ratajczak, Joanna, Doig, Craig L., Oakey, Lucy A., Callingham, Rebecca, Da Silva Xavier, Gabriella, Garten, Antje, Elhassan, Yasir S., Redpath, Philip, Migaud, Marie E., Philp, Andrew, Brenner, Charles, Canto, Carles, Lavery, Gareth G.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2017
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518663/
https://ncbi.nlm.nih.gov/pubmed/28752046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.05.011
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