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Synthesis of Oligodeoxynucleotides Containing a C8-2′-Deoxyguanosine Adduct Formed by the Carcinogen 3-Nitrobenzanthrone

This unit describes the detailed procedure for the synthesis of C8-2′-deoxyguanosine-3-aminobenzanthrone adduct located in a desired site in an oligonucleotide. The procedure has been described in five different parts. The synthesis of the protected 2′-deoxyguanosine, O(6)-benzyl-N(2)-DMTr-3′-5′-bis...

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Detalles Bibliográficos
Publicado en:Curr Protoc Nucleic Acid Chem
Main Authors: Chatterjee, Arindom, Malik, Chanchal K., Basu, Ashis K.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518617/
https://ncbi.nlm.nih.gov/pubmed/28628210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpnc.28
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