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SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING 2′-DEOXYGUANOSINE ADDUCTS OF NITROPYRENES

Two different approaches to synthesize oligonucleotides containing the 2′-deoxyguanosine adducts formed by nitropyrenes are described. A direct reaction of an unmodified oligonucleotide with an activated nitropyrene derivative is a convenient biomimetic approach for generating the major adducts in D...

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Detalhes bibliográficos
Main Authors: Colis, Laureen C., Chakraborti, Debasis, Hilario, Pablo, McCarty, Christopher, Basu, Ashis K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660736/
https://ncbi.nlm.nih.gov/pubmed/19219737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257770902736426
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