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Position and Length of Fatty Acids Strongly Affect Receptor Selectivity Pattern of Human Pancreatic Polypeptide Analogues
Pancreatic polypeptide (PP) is a satiety-inducing gut hormone targeting predominantly the Y(4) receptor within the neuropeptide Y multiligand/multireceptor family. Palmitoylated PP-based ligands have already been reported to exert prolonged satiety-inducing effects in animal models. Here, we suggest...
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| Publicado no: | ChemMedChem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5518309/ https://ncbi.nlm.nih.gov/pubmed/25156249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201402235 |
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