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High molecular weight PEGylation of human pancreatic polypeptide at position 22 improves stability and reduces food intake in mice
BACKGROUND AND PURPOSE: Human pancreatic polypeptide (hPP) is known to suppress appetite and food intake, thereby representing a potential therapeutic approach against obesity and associated metabolic disorders. The aim of this study was to improve hPP stability by covalent PEGylation with diverse m...
Tallennettuna:
| Julkaisussa: | Br J Pharmacol |
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| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
John Wiley and Sons Inc.
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5071565/ https://ncbi.nlm.nih.gov/pubmed/27545829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13582 |
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