Central nervous system uptake of intranasal glutathione in Parkinson’s disease

Glutathione (GSH) is depleted early in the course of Parkinson’s disease (PD), and deficiency has been shown to perpetuate oxidative stress, mitochondrial dysfunction, impaired autophagy, and cell death. GSH repletion has been proposed as a therapeutic intervention. The objective of this study was t...

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發表在:NPJ Parkinsons Dis
Main Authors: Mischley, Laurie K, Conley, Kevin E, Shankland, Eric G, Kavanagh, Terrance J, Rosenfeld, Michael E, Duda, John E, White, Collin C, Wilbur, Timothy K, De La Torre, Prysilla U, Padowski, Jeannie M
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516583/
https://ncbi.nlm.nih.gov/pubmed/28725693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjparkd.2016.2
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