Central nervous system uptake of intranasal glutathione in Parkinson’s disease

Glutathione (GSH) is depleted early in the course of Parkinson’s disease (PD), and deficiency has been shown to perpetuate oxidative stress, mitochondrial dysfunction, impaired autophagy, and cell death. GSH repletion has been proposed as a therapeutic intervention. The objective of this study was t...

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Detalhes bibliográficos
Publicado no:NPJ Parkinsons Dis
Main Authors: Mischley, Laurie K, Conley, Kevin E, Shankland, Eric G, Kavanagh, Terrance J, Rosenfeld, Michael E, Duda, John E, White, Collin C, Wilbur, Timothy K, De La Torre, Prysilla U, Padowski, Jeannie M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516583/
https://ncbi.nlm.nih.gov/pubmed/28725693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjparkd.2016.2
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