Central nervous system uptake of intranasal glutathione in Parkinson’s disease

Glutathione (GSH) is depleted early in the course of Parkinson’s disease (PD), and deficiency has been shown to perpetuate oxidative stress, mitochondrial dysfunction, impaired autophagy, and cell death. GSH repletion has been proposed as a therapeutic intervention. The objective of this study was t...

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Bibliografische gegevens
Gepubliceerd in:NPJ Parkinsons Dis
Hoofdauteurs: Mischley, Laurie K, Conley, Kevin E, Shankland, Eric G, Kavanagh, Terrance J, Rosenfeld, Michael E, Duda, John E, White, Collin C, Wilbur, Timothy K, De La Torre, Prysilla U, Padowski, Jeannie M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516583/
https://ncbi.nlm.nih.gov/pubmed/28725693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjparkd.2016.2
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