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Cell-type specific differences in promoter activity of the ALS-linked C9orf72 mouse ortholog
A hexanucleotide repeat expansion in the C9orf72 gene is the most common cause of inherited forms of the neurodegenerative disease amyotrophic lateral sclerosis (ALS). Both loss-of-function and gain-of-function mechanisms have been proposed to underlie this disease, but the pathogenic pathways are n...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5515847/ https://ncbi.nlm.nih.gov/pubmed/28720882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05864-2 |
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