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Emerging role of RNA•DNA hybrids in C9orf72-linked neurodegeneration

RNA plays an active role in structural polymorphism of the genome through the formation of stable RNA•DNA hybrids (R-loops). R-loops can modulate normal physiological processes and are also associated with pathological conditions, such as those related to nucleotide repeat expansions. A guanine-rich...

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Bibliografiska uppgifter
I publikationen:Cell Cycle
Huvudupphovsmän: Wang, Jiou, Haeusler, Aaron R, Simko, Eric AJ
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614400/
https://ncbi.nlm.nih.gov/pubmed/25590632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2014.995490
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