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Emerging role of RNA•DNA hybrids in C9orf72-linked neurodegeneration
RNA plays an active role in structural polymorphism of the genome through the formation of stable RNA•DNA hybrids (R-loops). R-loops can modulate normal physiological processes and are also associated with pathological conditions, such as those related to nucleotide repeat expansions. A guanine-rich...
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| Publié dans: | Cell Cycle |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4614400/ https://ncbi.nlm.nih.gov/pubmed/25590632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2014.995490 |
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