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Systemic deregulation of autophagy upon loss of ALS- and FTD-linked C9orf72
A genetic mutation in the C9orf72 gene causes the most common forms of neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The C9orf72 protein, predicted to be a DENN-family protein, is reduced in ALS and FTD, but its functions remain poorly understood....
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| Yayımlandı: | Autophagy |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5529072/ https://ncbi.nlm.nih.gov/pubmed/28319438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1299312 |
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