Cytochrome b(5) reductase and the control of lipid metabolism and healthspan

Cytochrome b(5) reductases (CYB5R) are required for the elongation and desaturation of fatty acids, cholesterol synthesis and mono-oxygenation of cytochrome P450 enzymes, all of which are associated with protection against metabolic disorders. However, the physiological role of CYB5R in the context...

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Pubblicato in:NPJ Aging Mech Dis
Autori principali: Martin-Montalvo, Alejandro, Sun, Yaning, Diaz-Ruiz, Alberto, Ali, Ahmed, Gutierrez, Vincent, Palacios, Hector H, Curtis, Jessica, Siendones, Emilio, Ariza, Julia, Abulwerdi, Gelareh A, Sun, Xiaoping, Wang, Annie X, Pearson, Kevin J, Fishbein, Kenneth W, Spencer, Richard G, Wang, Miao, Han, Xianlin, Scheibye-Knudsen, Morten, Baur, Joe A, Shertzer, Howard G, Navas, Placido, Villalba, Jose Manuel, Zou, Sige, Bernier, Michel, de Cabo, Rafael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515006/
https://ncbi.nlm.nih.gov/pubmed/28721264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjamd.2016.6
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