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Synthetic lethal interaction between the tumour suppressor STAG2 and its paralog STAG1

Cohesin is a multi-protein complex that tethers sister chromatids during mitosis and mediates DNA repair, genome compartmentalisation and regulation of gene expression. Cohesin subunits frequently acquire cancer loss-of-function alterations and act as tumour suppressors in several tumour types. This...

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書誌詳細
出版年:Oncotarget
主要な著者: Benedetti, Lorena, Cereda, Matteo, Monteverde, LeeAnn, Desai, Nikita, Ciccarelli, Francesca D.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514935/
https://ncbi.nlm.nih.gov/pubmed/28430577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16838
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