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MEGA-V: detection of variant gene sets in patient cohorts

SUMMARY: Detecting significant associations between genetic variants and disease may prove particularly challenging when the variants are rare in the population and/or act together with other variants to cause the disease. We have developed a statistical framework named Mutation Enrichment Gene set...

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Publicat a:Bioinformatics
Autors principals: Gambardella, Gennaro, Cereda, Matteo, Benedetti, Lorena, Ciccarelli, Francesca D
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408849/
https://ncbi.nlm.nih.gov/pubmed/28003259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw809
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