NFkB is essential for activin-induced colorectal cancer migration via upregulation of PI3K-MDM2 pathway

Colorectal cancer (CRC) remains a common and deadly cancer due to metastatic disease. Activin and TGFB (TGFβ) signaling are growth suppressive pathways that exert non-canonical pro-metastatic effects late in CRC carcinogenesis. We have recently shown that activin downregulates p21 via ubiquitination...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Jana, Arundhati, Krett, Nancy L, Guzman, Grace, Khalid, Ahmer, Ozden, Ozkan, Staudacher, Jonas J, Bauer, Jessica, Baik, Seung Hyun, Carroll, Timothy, Yazici, Cemal, Jung, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514916/
https://ncbi.nlm.nih.gov/pubmed/28418896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16343
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