Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB

NFkB activity is critical for survival and proliferation of normal lymphoid cells and many kinds of B-cell tumors, including multiple myeloma (MM). NFkB activating mutations, which are apparent progression events, enable MM tumors to become less dependent on bone marrow signals that activate NFkB. M...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Demchenko, Yulia N., Brents, Leslie A., Li, Zhihong, Bergsagel, Leif P., McGee, Lawrence R., Kuehl, Michael W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2014
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147345/
https://ncbi.nlm.nih.gov/pubmed/24980832
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak