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A critical role for the NFkB pathway in multiple myeloma

NFkB transcription factors play a key role in the survival and proliferation of many kinds of B-cell tumors, including multiple myeloma (MM). It was shown that NFkB activation in MM tumors results mainly from extrinsic signaling by APRIL and BAFF ligands that stimulate receptors on normal plasma cel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Demchenko, Yulia N., Kuehl, W. Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947827/
https://ncbi.nlm.nih.gov/pubmed/20890394
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