Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB

NFkB activity is critical for survival and proliferation of normal lymphoid cells and many kinds of B-cell tumors, including multiple myeloma (MM). NFkB activating mutations, which are apparent progression events, enable MM tumors to become less dependent on bone marrow signals that activate NFkB. M...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Demchenko, Yulia N., Brents, Leslie A., Li, Zhihong, Bergsagel, Leif P., McGee, Lawrence R., Kuehl, Michael W.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147345/
https://ncbi.nlm.nih.gov/pubmed/24980832
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars