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Human ribosomal P1-P2 heterodimer represents an optimal docking site for ricin A chain with a prominent role for P1 C-terminus

The eukaryotic P-stalk contains two P1-P2 protein dimers with a conserved C- terminal domain (CTD) critical for the interaction with external factors. To understand the role of the individual CTD of human P1/P2 proteins, we examined the interaction of reconstituted human P-protein complexes and C-te...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Grela, Przemysław, Li, Xiao-Ping, Horbowicz, Patrycja, Dźwierzyńska, Monika, Tchórzewski, Marek, Tumer, Nilgun E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514047/
https://ncbi.nlm.nih.gov/pubmed/28717148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05675-5
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