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Pentameric Organization of the Ribosomal Stalk Accelerates Recruitment of Ricin A Chain to the Ribosome for Depurination

Ribosome inactivating proteins (RIPs) depurinate a universally conserved adenine in the α-sarcin/ricin loop (SRL) and inhibit protein synthesis at the translation elongation step. We previously showed that ribosomal stalk is required for depurination of the SRL by ricin toxin A chain (RTA). The inte...

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書誌詳細
主要な著者: Li, Xiao-Ping, Grela, Przemyslaw, Krokowski, Dawid, Tchórzewski, Marek, Tumer, Nilgun E.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009872/
https://ncbi.nlm.nih.gov/pubmed/20974854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.171793
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