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Functional divergence between the two P1-P2 stalk dimers on the ribosome in their interaction with ricin A chain

The eukaryotic stalk, which is responsible for the recruitment of translation factors, is a pentamer containing two P1–P2 dimers with unclear modes of action. In Saccharomyces cerevisiae, P1/P2 proteins (individual P1 and P2 proteins) are organized into two distinct dimers, P1A–P2B and P1B–P2A. To i...

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Detalhes bibliográficos
Main Authors: Grela, Przemysław, Li, Xiao-Ping, Tchórzewski, Marek, Tumer, Nilgun E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100481/
https://ncbi.nlm.nih.gov/pubmed/24576056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140014
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