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Early and Delayed Antiretroviral Therapy Results in Comparable Reductions in CD8(+) T Cell Exhaustion Marker Expression
In untreated HIV infection, CD8(+) T cell exhaustion (i.e., decreased proliferative and effector capacity) is associated with high levels of expression of coinhibitory receptors, including PD-1, T cell immunoreceptor with Ig and ITIM domains (TIGIT), CD160, and 2B4. This is evident for both HIV-spec...
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| Publicat a: | AIDS Res Hum Retroviruses |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Mary Ann Liebert, Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5512309/ https://ncbi.nlm.nih.gov/pubmed/28335609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2016.0324 |
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