The role of hypoxia on the acquisition of epithelial-mesenchymal transition and cancer stemness: a possible link to epigenetic regulation

A hypoxic microenvironment leads to cancer progression and increases the metastatic potential of cancer cells within tumors via epithelial-mesenchymal transition (EMT) and cancer stemness acquisition. The hypoxic response pathway can occur under oxygen tensions of < 40 mmHg through hypoxia-induci...

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Vydáno v:Korean J Intern Med
Hlavní autoři: Yeo, Chang Dong, Kang, Nahyeon, Choi, Su Yeon, Kim, Bit Na, Park, Chan Kwon, Kim, Jin Woo, Kim, Young Kyoon, Kim, Seung Joon
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Association of Internal Medicine 2017
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511947/
https://ncbi.nlm.nih.gov/pubmed/28704917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3904/kjim.2016.302
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